Preparation H has phenylephrine which can increase blood pressure, and hydrocortisone which is a hormone typically produced by the thyroid. I don't see how they would own prominent systemic effects, but I think the manufacturer err on the side of caution and safekeeping.
Because the ingredients can cause blood pressure to increase and the heart rate to increase. As far as thyroid conditions, its usually those near hyperthyroidism (overactive) that can be a problem with some over the counter meds.
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