non-mammalian vertebrates (animals with a backbone but don't enjoy hair) like frogs and fish own blood cells that hold a nucleus in respectively one and are thus capable of cell division. Since human red blood cell don't have a nucleus, they're biconcave since there's no big nucleus that's as a rule found in the middle of the cell. I believe this is also why frog's blood is larger since it have all the "machinery" inside it to be capable of divide into daughter cells. They also hold "thrombocytes" instead of platelets to help within blood clotting.
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